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DeCS
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Descriptor English:
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DNA Topoisomerases, Type I
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Descriptor Spanish:
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ADN-topoisomerasas de tipo I
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Descriptor Portuguese:
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DNA Topoisomerases Tipo I
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Synonyms English:
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DNA Nicking-Closing Protein
DNA Nicking-Closing Proteins
DNA Relaxing Enzyme
DNA Relaxing Enzymes
DNA Relaxing Protein
DNA Topoisomerase
DNA Topoisomerase I
DNA Type 1 Topoisomerase
DNA Untwisting Enzyme
DNA Untwisting Enzymes
DNA Untwisting Protein
DNA Untwisting Proteins
Topoisomerase I
Type I DNA Topoisomerase
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Tree Number:
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D08.811.399.403.483
D12.776.157.687.375
D12.776.660.720.375
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Definition English:
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DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix. |
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Indexing Annotation English:
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do not confuse entry term DNA UNTWISTING PROTEIN with DNA UNWINDING PROTEINS see DNA HELICASES; coordinate with BACTERIAL PROTEINS or ARCHAEAL PROTEINS if pertinent
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Entry Combination - descr/qualif English:
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DNA Topoisomerases, Type I/antagonists & inhibitors use Topoisomerase I Inhibitors
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History Note English:
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2002
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Allowable Qualifiers English:
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Record Number:
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31732
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Unique Identifier:
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D004264
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Occurrence in VHL:
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Similar:
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DeCS
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